Author ' s response to reviews Title : Adherence with tobramycin inhaled solution and health care utilization

Adherence with tobramycin inhaled solution and health care utilization

BACKGROUND Adherence with tobramycin inhalation solution (TIS) during routine cystic fibrosis (CF) care may differ from recommended guidelines and affect health care utilization. METHODS We analyzed 2001-2006 healthcare claims data from 45 large employers. Study subjects had diagnoses of CF and at least 1 prescription for TIS. We measured adherence as the number of TIS therapy cycles complete...

Author ' s response to reviews Title : Assessing the context of health care utilization in Ecuador : A spatial and multilevel analysis

TITLE: Inhaled Tobramycin versus Intravenous Tobramycin for Patients with Cystic Fibrosis: A Review of the Clinical Effectiveness, Cost Effectiveness, and Guidelines

Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered along with other types of information and health care considerations. The information inclu...

TITLE: Inhaled Tobramycin versus Intravenous Tobramycin for Patients with Cystic Fibrosis: A Review of the Clinical Effectiveness, Cost Effectiveness, and Guidelines

Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered along with other types of information and health care considerations. The information inclu...

Adherence to tobramycin inhaled powder vs inhaled solution in patients with cystic fibrosis: analysis of US insurance claims data

PURPOSE Tobramycin inhalation powder (TIP), the first dry-powder inhaled antibiotic for pulmonary Pseudomonas aeruginosa infection, is associated with reduced treatment burden, increased patient satisfaction, and higher self-reported adherence for cystic fibrosis (CF) patients. We compared adherence in CF patients newly treated with TIP with those newly treated with the traditional tobramycin i...